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Corning commercializes new Synthemax synthetic surface for supporting growth and differentiation of stem cells

March 01, 2016

Stable doubling time; Phenotypic marker expression (Oct4, TRA-1-60, SSEA4); Retention of normal karyotype; and Maintenance of pluripotency.

Since 2006, Corning has worked with Geron to develop synthetic surface matrices to support the scalable manufacturing of stem cells and derived differentiated cell types (e.g., cardiomyocytes). Synthetic growth surfaces could replace the biological surface coatings that are widely used today to grow and differentiate pluripotent stem cells and may offer increased reproducibility, cost savings, and regulatory advantages.

Laboratory products using specialized surfaces, such as the Synthemax surface, are being commercialized by Corning. Currently, Corning??ôs six-well plate with the Corning Synthemax surface is available in North America.

Source Corning Incorporated