Wellstat Therapeutics and Sanofi-Aventis to develop, manufacture and commercialize PN2034

November 28, 2015

-- Use gentle cleaning routines. Wash feet (do not soak them) in lukewarm water, never hot. Wash with soft cloth and mild soap. -- Dry thoroughly but gently between the toes. Use a moisturizing lotion for dry skin, but do not use in between the toes. Keep dry skin soft and pliable. -- Trim nails straight across with a nail clipper. Do not round the corners. -- Reduce calluses with gentle daily rubbing with a foot file or pumice stone. Rub in one direction to avoid tearing the skin. Never trim with a sharp razor blade or apply liquid callus removers. -- Choose good footwear with cushioned soles and uppers made of soft, breathable material such as leather, not plastic. -- Avoid wearing sandals and never walk barefoot. -- Wear cotton or natural fiber socks for the best padding. Avoid synthetic materials. Don't wear socks with holes. Do not wear socks with elastic tops that can cut off circulation. -- Break in new shoes gradually. Wear them one or two hours at a time. -- Patients with neuropathy should use custom-molded insoles to help cushion the foot.

"Patients should urgently be examined by an orthopaedic foot and ankle surgeon whenever they develop a new ulcer, redness or acute onset of pain and swelling. Based on the AOFAS 'Guidelines for Diabetic Foot Care,' published in FAI in 2005, patients should have an ongoing program of evaluation by a healthcare professional," says Pinzur.

The good news is the care of the lower extremities in diabetic individuals has improved in the last several years. But the key to success is prevention. Taking responsibility for good foot hygiene, wearing sensible footwear, and careful daily inspection of feet are life-long steps to help prevent and avoid future foot complications.

Public education resources on the care and treatment of the diabetic foot may be found on the AOFAS website www.aofas by clicking on Patient Education & Resources, then Ailments and Conditions. The site also features a surgeon referral service; making it easy for diabetic patients to find a local orthopaedic surgeon specializing in foot and ankle care.